If the device is recognized but audio quality is poor:
Yes, you can use the Polycom C100s on Windows 10. No, you shouldn't search for a dedicated driver. Use the Microsoft inbox driver, fix your privacy settings, and enjoy that vintage Polycom audio clarity while it lasts. Polycom Communicator C100s Windows 10 Driver
Step-by-Step Instructions to Make the C100s Work on Windows 10 If the device is recognized but audio quality
If you follow the generic driver selection method in Device Manager and adjust your sound settings to 16-bit, 44100 Hz, your legacy C100s will likely function for conference calls. However, given the age of the hardware and the ever-evolving nature of Windows 10 (and 11), consider upgrading to a modern speakerphone to avoid constant troubleshooting. Step-by-Step Instructions to Make the C100s Work on
How to Install and Use the Polycom Communicator C100s on Windows 10
: While audio (mic/speaker) may work, the physical buttons on the device (Skype launch, answer/hang up) were built specifically for the Skype API and may not function with modern versions of Microsoft Teams, Zoom, or the current Skype desktop app.